Sequoyah is the better team. Compare the other division games this season it becomes obvious, with Sequoyah only letting one touchdown score in three division games. Sweetwater had double overtime with Meigs at home, Sequoyah shut them out at Meigs!
However, historically, Sweetwater has beat Sequoyah even when Sequoyah were the favorites to win. As long as Sequoyah doesn't choke, they should be fine. I predict Sequoyah 24, Sweetwater 7