Murphy has had teams that could have matched up athlete wise with this SP team and have beat teams with more speed and athletes than South Pitt will put on the field Friday in the past (Albemarle, Mountain Island, Plymouth, etc.) but that's irrelevant as far as Friday goes, this isn't those Murphy teams.
With that said I think Murphy could keep things interesting Friday for a bit with their size upfront and the power run game, I think in the end South Pitt's talent and athlete advantage wins out. Murphy will likely struggle on D, this is one of the weakest secondaries Murphy has ever fielded and Murphy is deficient at middle linebacker, too much youth and a lack of speed.